Question: What Kind Of Disease Is CMT?

What does a Charcot foot look like?

When the midfoot is involved in Charcot foot, the arch collapses, which rounds the bottom of the foot.

This is called a rocker-bottom foot deformity.

Depending on the location of the bone break, the toes can start to curve under like claws or the ankle can become deformed and unstable..

Can CMT be prevented?

There is no cure for CMT and it can’t be prevented. Treatment usually involves a combination of physical therapy, occupational therapy, moderate exercise, leg braces, and shoe inserts. In some cases, surgery may be performed to correct foot or joint deformities.

Why is it called Charcot Marie Tooth disease?

Charcot-Marie-Tooth disease (CMT) is a spectrum of nerve disorders named after the three physicians who first described it in 1886 — Jean-Martin Charcot and Pierre Marie of France and Howard Henry Tooth of the United Kingdom.

Does CMT affect your brain?

Unlike other neurological disorders, CMT usually isn’t life-threatening, and it almost never affects the brain. It causes damage to the peripheral nerves — tracts of nerve cell fibers that connect the brain and spinal cord to muscles and sensory organs.

Does CMT affect memory?

The most common cause of CMT is the duplication of a region on the short arm of chromosome 17, which includes the gene PMP22. We report a thirty-seven-year-old man with CMT disease having sleep, memory and attention disorders characterized by brief retrograde amnesia at early age.

How do you fix a Charcot foot?

Non-surgical treatment for Charcot foot consists of:Immobilization. Because the foot and ankle are so fragile during the early stage of Charcot, they must be protected so the weakened bones can repair themselves. … Custom shoes and bracing. … Activity modification.

How many types of CMT are there?

Types of Charcot-Marie-Tooth Researchers have identified mutations in more than 100 unique genes that cause CMT, but the vast majority of people with CMT (90%) have one of four types: CMT1A, CMT1B, CMT2A or CMTX1.

Is there a blood test for CMT?

Genetic testing. These tests, which can detect the most common genetic defects known to cause Charcot-Marie-Tooth disease, are done by blood sample. Genetic testing may give people with the disorder more information for family planning.

Is Charcot Marie Tooth autoimmune?

The phenotypic features encompasses neurological alterations similar to those observed in the axonal type 2 form of Charcot-Marie-Tooth disease (CMT2) and include autoimmune manifestations.

Is CMT a type of muscular dystrophy?

No, CMT is not a type of muscular dystrophy. CMT is primarily a disease of the peripheral nerves, whereas muscular dystrophy is a group of diseases of the muscle itself.

How bad can CMT get?

Complications of Charcot-Marie-Tooth disease vary in severity from person to person. Foot abnormalities and difficulty walking are usually the most serious problems. Muscles may get weaker, and you may injure areas of the body that experience decreased sensation.

Is CMT more common in males or females?

The condition affects an equal number of males and females. CMT hereditary neuropathy is the most common inherited neurological disorder affecting more than 250,000 Americans. Since this condition is frequently undiagnosed, misdiagnosed or diagnosed very late in life, the true number of affected persons may be higher.

Does CMT cause back pain?

And, because joints often have more stress put on them because of weak muscles (weak ankles etc), then knees and hips have to do more work in people with CMT. Therefore, in my experience, arthritic pain and joint as well as back surgery are more frequent in patients with CMT.

What type of disease is CMT?

Charcot-Marie-Tooth disease (CMT) is one of a group of disorders that cause damage to the peripheral nerves—the nerves that transmit information and signals from the brain and spinal cord to and from the rest of the body, as well as sensory information such as touch back to the spinal cord and brain.

Is CMT considered a disability?

Medically Qualifying Under A Disability Listing: CMT is a form of peripheral neuropathy, meaning it affects the nerves and muscles in the arms, legs, hands, and feet. The Social Security Administration (SSA) has a standard disability listing for this type of neurological disorder.

At what age does CMT present?

The age of onset of CMT can vary anywhere from young childhood to the 50s or 60s. Symptoms typically begin by the age of 20. For reasons unknown as of 2004, the severity in symptoms can also vary greatly, even among members of the same family .

Can CMT make you tired?

Fatigue is a common symptom in CMT. A study, published in the Journal of Neurology in 2010 and based on questionnaire given patients and an age- and sex-matched control group, reported that fatigue levels were significantly higher in people with CMT. Fatigue in CMT can be due to a number of reasons.

Does CMT cause pain?

Paradoxically, despite sensory loss, some people with CMT experience pain — a combination of painful muscle cramps and neuropathic pain. This pain is not caused by an external trigger but by defective signals in sensory axons. Both types of pain usually can be alleviated with medication.

Can CMT affect your eyes?

Testing of nerves for their ability to carry electrical signals reveals that they are severely impaired. Affected individuals also may have an abnormally high pressure in the eye and they suffer severe damage to their optic nerves. This may occur in infancy or as juveniles.

Can CMT be passed from father to daughter?

This change is called a mutation. Some genetic mutations are hereditary, meaning they can be passed down from a parent to their child. CMT is caused by hereditary genetic mutations. But just because someone has CMT doesn’t mean they got it from one of their parents.